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In vitiligo patients, an increase in pro-inflammatory cytokines typical of innate immunity, IL IL-1, IL-1, IL-6, IL-8, IL-12, IL-15, and TNF-, is observed in both serum and skin.2,3 Damage-associated molecular patterns The Koebner phenomenon is considered an initial trigger for vitiligo
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On the other hand, the enzymatic activity of glutathione synthetase increased steadily in wheat tissue at the feeding site in resistant plants starting from three hours after Hessian fly infestation (Figure 2a)
However, paresthesias is also a common symptom of nerve damage caused by high blood sugar in people with diabetes this is called diabetic peripheral neuropathy