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The authors also demonstrated an important role for CGRP in maintaining airway progenitor cells, which they speculated might be important for lung injury and repair in CF airways

151 While preclinical/clinical studies suggest that the dual/pan-PPAR agonists have a more significant effect in the treatment of disease when compared with PPAR or PPAR agonists alone, improvement of the low agonistic activity and low metabolic stability of multiple agonists may still need to be improved

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