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Lactate accumulation within the tumor microenvironment suppresses effector T cell proliferation and cytotoxic activity via GPR81-mediated signaling and metabolic competition, while simultaneously polarizing tumor-associated macrophages toward an immunosuppressive M2 phenotype that promotes tumor progression (8)

This Research Topic is part of a series with: The changing faces of glutathione, a cellular protagonist., Volume II Glutathione (GSH) has been described for a long time just as a defensive reagent against the action of toxic xenobiotics (drugs, pollutants, carcinogens), both directly and as a cofactor for GSH transferases

Food poisoning can lead to excessive dehydration and fatigue

If external signs of ageing appear on your face, it might be an indication of declining glutathione levels

Breakfast is often the weakest protein meal of the day: a piece of toast, a bowl of cereal, a banana on the go

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