Studies demonstrate statistically significant improvements in cellular physiological function across multiple organs
2025;doi:10.1001/jama.2025.21056 Wu JH, Lemaitre RN, King IB, et al
The data are publicly available at the Metabolonote database ( https:/repository.massbank.jp/ )
5.2 Dose effect and safety issues 5.2.1 Dose-dependent safety concerns for functional food active ingredients Emerging evidence reveals significant population-specific toxicity risks for several widely consumed functional food ingredients, with genetic factors, smoking status, and concurrent medications dramatically altering safety profiles (239)
These include hyperpigmentation, jaundice, vitiligo, and angular stomatitis (cracked mouth corners)
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