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Studies using a dextran sulfate sodium-induced colitis mouse model showed that Parasutterella was a harmful bacterium and that diet modification (Li et al., 2022) or crocetin (Dang et al., 2022) could decrease the abundance of Parasutterella

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Ive worked with hundreds of clients to help them change their diets, better manage their flares, and find relief

a recent safety analysis found no anaphylaxis in hundreds of patients receiving high-dose IV thiamine, suggesting the risk is very low in practice

However, the epigenetic memory effects of such interventions in germ cells, as well as their potential long-term impact on offspring safety, require systematic evaluation in preclinical and clinical settings