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The nutritional dependency for haem/iron at all stages of NTHi pathogenesis exposes a vulnerability that may be exploited for the development of such therapies

Even when fertilization is achieved, oxidative stress (inflammation)-induced apoptosis (cell death) may result in embryo fragmentation implantation failure insufficient luteal hormonal levels miscarriage impaired placenta development inadequate growth of the uterine lining (necessary for embryo development congenital abnormalities More reproductive condition-specific