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Management, therefore, focuses on identifying elevated Lp(a), intensifying control of all modifiable risk factors, lowering LDL-C or ApoB aggressively when appropriate, and considering PCSK9 inhibitor therapy in selected high-risk patients because monoclonal PCSK9 inhibitors modestly lower Lp(a) while substantially lowering LDL-C

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There were no interaction effects of the nutritional states and L-carnitine found in the whole fish lipid level and TG content in the different organs, except in the BBOX1 mRNA level (Supplemental Table 1), showing BBOX1 is simultaneously regulated by nutritional state and L-carnitine supplementation

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