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The public docket (FDA-2025-N-6895) is open for written comments at regulations.gov

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IGF is a central player in changing the fate of cells during survival and proliferation through the modulation of leading signaling pathways, including Jak/STAT, MAP kinase/ERK, and PI3K/Akt, and subsequent impacts on steroidogenesis and cell division

[DOI] [PubMed] [Google Scholar] 163.Schultz ST, Gould GG