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The convenience factor shouldnt be overlooked either

If you have any sort of GI issue (GERD, reflux, SIBO/SIFO, yeast problems, chronic constipation, etc.) you will have problems taking oral forms of vitamin B12

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Mechanistic Focus in Research Within experimental laboratory settings, 5-Amino-1MQ is commonly studied in relation to metabolic signalling pathways

[21] When treated with cyanocobalamin, patients with Leber's disease may develop serious optic atrophy, possibly leading to blindness, based on few case reports

The well-known geriatrician-haematologist Larry Solomon, working at Yale University in the USA, wrote 20 years ago: if I had treated only those people who actually had too low serum B12 and elevated MMA values, then I would not have treated approximately two-thirds of the people with a favourable response to B12 supplementation (note: partly via injections, partly via oral supplementation)