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Contributions of neuroimmune interactions to chemotherapy-induced peripheral neuropathy development and its prevention/therapy

10.1038/sj.onc.1208940 Oncogene 139 NzouG.WicksR

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A healthy immune system is balancedable to mount a powerful defense against pathogens while not overreacting and causing chronic inflammation or autoimmunity

Thus, m 6 A reduces RNA reactogenicity by suppressing its binding to innate immune receptors (RIG-I, TLR3, TLR7, TLR8) that recognize exogenous RNA

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