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Tirzepatide is a glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for type 2 diabetes management and chronic weight management

Methods Materials For NMR spectra of compounds in this manuscript, see Supplementary Figs 1473

Copper-based metal-organic framework overcomes cancer chemoresistance through systemically disrupting dynamically balanced cellular redox homeostasis

Under NIR irradiation, GASs therapeutic function was activated to exert anti-AD effects by degrading A, inhibiting A aggregation, and decomposing A fibers

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Obesity induces various cellular stress responses, leading to cellular senescence and the accumulation of senescent cells in adipose tissue and other organs (Figure 4)