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ABCC5s primary biological role is to expel xenobiotics and certain endogenous metabolites from cells

By using a small-molecule inhibitor of tankyrase, XAV939, they showed stabilization of axin and downregulation of Wnt signaling (Liu et al., 2007

5A), we hypothesized that Cyss mediates protein stabilization of NRF2 and that KEAP1 is involved in sensing intracellular Cyss levels by direct cysteinylation of its sensor Cys residues

Han C, Deng Y, Xu W, Liu Z, Wang T, Wang S, Liu J, Liu X

Regular physical activity, such as cardio and resistance training, synergizes with L-carnitines ability to enhance fatty acid oxidation, promoting greater calorie expenditure and fat loss