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The dermatitis score was evaluated the day after each DNCB application based on five symptoms: erythema/edema, dryness, erosion, excoriation, and lichenification, and each of the symptoms has 0 (none), 1 (mild), 2 (moderate), and 3 (severe) scores based on the skin lesion level ( Scratching behavior To investigate AD-like behavioral changes, the time of mice scratching the ear and dorsal skin in the hind paw for 30 min was measured after DBCB application, which was scored 0 (none), 2 (scratching shorter than 1.5 s), 4 (scratching longer than 1.5 s) ( Histological examination For histological analysis, paraffin-embedded tissues were sectioned at 4 m

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