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En un estudio piloto temprano, bajo aplicacion topica de un complejo de cobre-tripeptido, 7 de 10 participantes mostraron un aumento de la sintesis de procolageno, frente a 5 de 10 con vitamina C y 4 de 10 con tretinoina (acido retinoico) como sustancias de referencia (Abdulghani et al., 199800011-4))

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Drugs Pentadecapeptide BPC 157 (manufactured by Diagen, Ljubljana, Slovenia ( Procedure Before retrobulbar application and/or fundus imaging (filmed with USB microscope camera Veho Discovery VMS-004 Deluxe and VOLK Digital Wide Field Lens for indirect ophthalmoscopy), the animals were deeply anesthetized with diazepam (5 mg/kg b.w