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Free Radical Biology and Medicine , 30 (11), 11911212

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We demonstrate applicability beyond 5FU treatment in CRC to any TS-targeted therapeutics in other disease subtypes

Current safety data for 5-amino-1MQ appears favorable for short-term use (8-12 week cycles), with no significant toxicity observed in preclinical studies at therapeutic doses

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10.1080/1040841x.2016.1192578 Crit