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and Muller, G.A

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With Free radicals being the overarching enemy, an imbalance is created creating a negative outcome, of wrinkles, inflammation, hyperpigmentation, and melasma

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Second, not only environmental factors such as 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and rotenone but also familial genes such as SNCA (PARK1), Parkin (PARK2) and DJ-1 (PARK7) lead to PD pathogenesis partially by inducing overwhelming ROS production 6,7,8

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