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Graphical Abstract Similar content being viewed by others Introduction Premature ovarian insufficiency (POI), whether idiopathic or resulting from chemotherapy-induced ovarian failure (CIOF), poses a significant threat to the reproductive and endocrine health of women globally [1, 2]

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After first puncture, refrigerate and use within 28 days

Mutations in SDHC cause autosomal dominant paraganglioma, type 3