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Conversely, in the higher regions of the brain such as the forebrain, glycine takes on an excitatory role as an obligatory co-agonist at N-methyl-D-aspartate (NMDA) receptors

Zhang Q, Han L, Shi C, Jacamo R, Pan R, John MMC, Jeremy R, Kurtz S, Mu H, Ruvolo V, Ma H, Andreeff M , Mi Y, Tyner J, Leverson J, Letai A, Davis RE, Konopleva M

C.TripathyP.MishraN.SinghS.ChoudhariP.et al

These investigations continue to contribute valuable knowledge regarding peptide-mediated biological communication systems

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445 Interestingly, the mRNA expression levels of CREB, PGC-1, NRF-1, NRF-2, and TFAM are decreased as early as 1 month of age when there is no significant A oligomer deposition in 3xTg-AD mouse (harboring PS1, APP, and tau human transgenes)