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Higher ambient temperatures contribute to heat stress for residents, potentially leading to adverse health effects (heat exhaustion, heat stroke, exacerbated medical conditions) and reduced outdoor comfort (Tamball et al 2024)

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79,87 Activation of the serine synthesis pathway correlates directly with glutathione synthesis, 87 as serine-derived glycine is one of the components of glutathione

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It converts two GSH molecules into oxidized glutathione (GSSG), and reduces lipid peroxide (PEs-AA/ADA-OOH) to the non-toxic corresponding lipid derived alcohol (PEs-AA/ADA-OH) to prevent the accumulation of harmful lipid peroxides (Maiorino et al

Remember, pyridoxine is a supportive tool, not a guaranteed cure for nausea