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Kiriyama K, Hara KY, Kondo A

Ital J Pediatr 49 , 80 (2023)

Jaganjac et al., 2020

Authors concluded that, in the process of prostate carcinogenesis, activating histone modifications on GSTP1 are lost and subsequently DNA becomes methylated and inaccessible resulting in transcriptional silencing thus demonstrating interplay between histone reprogramming and promoter region methylation (Okino et al., 2007)