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Collectively, this study provides a solid foundation for future exploration into the impact of NNMTi-and diet-mediated changes to the gut microbiome in obese and lean populations, as well as future targets to investigate mechanistically with NNMTi treatment

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PKA-dependent phosphorylation of perilipin A may facilitate interaction with HSL on the lipid droplet, thereby increasing activity of the enzyme (84)

STAT5 is required for lipid breakdown and beta-adrenergic responsiveness of brown adipose tissue

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