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Acknowledgements This work was partly supported by Associazione Italiana Ricerca sul Cancro (AIRC) (IG2014-15197 to L.F.) and by grants from the University of Chieti-Pescara G

However, evidence is still limited and more human research is needed

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64, 825838.10.1111/j.1365-313X.2010.04371.x 64 WachterA.WolfS.SteiningerH.BogsJ.RauschT

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It has been well documented that sepsis occurs because of over-activated immune responses which include intractable inflammatory responses associated with imbalanced cytokine production (56, 57)