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Reconstitution volume, vial concentration and injection frequency all interact with the intended mg/kg figure, and small arithmetic errors compound across a study arm

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the three conditional equilibrium constants are in equations (1)(3), (the symbols in square brackets mean total concentration, which actually are the sum of the concentration of all microspecies of the compound in question): In order to get a clear insight into the redox equilibria, purified from the protonation effects, an improved evaluation method was introduced to determine the species-specific redox equilibrium constants ( k 1 , k 2 , k 3 ) 14