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Reduced CSF concentrations have been described in patients with schizophrenia

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Both studies administered B12 i.m., one used methyl-B12 at a dose of 500 g three times per week for 2 weeks, 63 the other used cyano-B12, 1000 g daily for 2 weeks

We are also interested in the correlated changes across all three modalities, as the comparison between brain metabolism and function has important implications for medical imaging biomarkers, both when metabolism and function are correlated [27] and also when they diverge [28]