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Bibcode:2005PNAS..10211278M

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These MET agonists include anti-MET monoclonal antibodies based on the bivalent characteristic of antibodies (Prat et al., 1998

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Conventional thinking posits that a primary defect in adaptive immunity promotes recruitment and entry of peripherally activated lymphocytes into the CNS across a disrupted bloodbrain barrier where a complex cascade of autoimmune/inflammatory processes culminates in edema, and destruction of myelin, axons and oligodendrocytes (for detailed reviews see Dendrou et al., 2015

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