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These nuclear respiratory factors are primarily tasked with governing the expression of mitochondrial respiratory genes (proteins), key mitochondrial enzyme transcription, coding genes for mitochondrial respiratory complex subunits, mitochondrial translation components, and heme biosynthase (Dinkova-Kostova and Abramov, 2015

Sheng Y, Yang X, Lian Y, Zhang B, He X, Xu W, Huang K

Oncogene 40 , 23392354 (2021)

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Dreiem A, Gertz C, Seegal R (2005) The effects of methylmercury on mitochondrial function and reactive oxygen species formation in rat striatal synaptosomes are age-dependent