High neuronal chloride is essential for interneuron precursors migration from ganglionic eminences to the dorsal region of the telencephalon (also known as pallium)
Clin Pharmacol Ther 100(5):464478
Looijer-van Langen M, Veldhuyzen van Zanten S
Muscle Recovery : BCAAs reduce muscle damage, decrease delayed onset of muscle soreness (DOMS), and accelerate recovery after intense workouts
administration of agonist MR-409 to mice bearing xenografts of lung cancers significantly inhibited tumor growth after treatment of 48 weeks 67
Early phase reflecting nicotinic stimulation (CNS, Parasympathetic & Sympathetic) (first 15 mins to an hour): nausea & vomiting a result of parasympathetic stimulation of the GI tract, causing increased tone and motility, resulting in nausea, vomiting, diarrhea, and voiding of urine (Vanderah & Pappano, 2021)