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Abbreviations: CNS, central nervous system

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Another TKI, gefitinib (ZD1839, Iressa), which targets the epidermal growth factor receptor (EGFR), has been shown to restrict M.tb replication in both macrophages as well as in the lungs of M.tb -infected mice by promoting the host autophagy pathway through the inhibition of the p38 MAPK signaling pathway activated by EGFR [10]

Sulforaphane prevents angiotensin II-induced cardiomyopathy by activation of Nrf2 via stimulating the Akt/GSK-3ss/Fyn pathway. Redox Biology 15 (2018): 405-417