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Advanced techniques like CRISPR gene-editing technology have further enhanced the precision of in vivo models, allowing the replication of specific mutations linked to AD (Bhardwaj et al., 2022)
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As the intestinal microbiota after eradication differed from the H
These findings shed light on mechanisms underlying 5FU resistance and propose a rational strategy for combination therapy in CRC, emphasizing the potential clinical benefit of targeting mitochondrial metabolism to overcome resistance and enhance patient outcomes