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Notably, in this model system, the survival of control HaCaT cells after UV exposure did not seem to rely on GSTP1 in the absence of HPV-16 E7 expression
TABLE 1 Summary of mechanisms leading to tamoxifen resistance The Discovery of LEM4 and the Association Between Cell Cycle Regulators and Resistance to Tamoxifen As a competitive antagonist of estradiol, tamoxifen can bind to estrogen receptors in competition with estradiol and form a stable complex, which inhibits the transcription activity of the estrogen receptor and blocks breast cancer cells in G1 phase to inhibit tumor proliferation
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Vitamin C plays many essential roles in the body, including the biosynthesis of natural chemicals and proteins such as neurotransmitters, L-carnitine, and collagen
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P values indicated, calculated by one-way ANOVA with Dunnetts multiple comparisons test ( a,c ), two-tailed t -test ( b ) or two-way ANOVA with dks multiple comparisons test
