During the evolution of Cyanobacteria and Proteobacteria, GSH-dependent ROS detoxification systems incorporated enzymes that play crucial roles in these mechanisms and use GSH as a cofactor, such as GSH peroxidases, GSH reductases, glutaredoxins, and GSH-S-transferases [41]
During this time, you can relax while the glutathione works its magic
Glutathione is the mother of all antioxidants, the master detoxifier of the immune system: Glutathione (pronounced gloota-thigh-on)
It was like, right afterwards
When mitochondria, the organelles in cells that power our bodies, process oxygen, between 1% and 2% gets left behind as free radicals known as reactive oxygen species
MOTS-c, by contrast, works from the inside of the mitochondria outward, activating the same primordial energy-sensing cascade that millions of years of evolution have refined into the body's most fundamental metabolic regulator