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Furthermore, increased E2 production can maintain follicular structure and performance, leading in greater follicle growth [14] (Fig
Conclusions Changes in intra-portal insulin levels play an intricate yet permissive role in the regulation of the GH/IGF-I axis by either stimulating or suppressing hepatic GH sensitivity and hepatic IGF-I generation, probably via an insulin-mediated regulation of the hepatic GHR expression
