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BPTES) or SLC1A5 (GPNA), the key enzyme and glutamine transporter whose activities are crucial for the process ( Figure 4a ), substantially rescued the viability of Erastin-treated LDHB KD A549 cells ( Figure 4e ), indicating that LDHB KD/Erastin inhibits cell viability through glutaminolysis

The American biochemist Loren Pickart discovered it in 1973 when he observed that liver tissue from older patients exhibited improved protein synthesis in the presence of plasma from younger donors

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J Phys Chem C 113:1773017736