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454 The ongoing phase IIb VIVIAD trial (NCT04498650) aims to further explore its long-term safety, tolerability, effects on cognition, and impact on AD biomarkers

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Blood samples from the inferior cava vein were obtained for biochemical assays

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doi: 10.3389/fendo.2026.1766838 Received 13 December 2025 Revised 20 January 2026 Accepted 26 January 2026 Published 10 February 2026 Volume 17 - 2026 Edited by Duan Xing, Southeast University, China Reviewed by Sandeep Das, Louisiana State University Health Shreveport, United States Fatimah Usman, Sriwijaya University, Indonesia Updates Copyright 2026 Natarajan, E