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According to Harvard Health, B12 deficiency can be sneaky and harmful often developing silently over years before symptoms become apparent

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Vitamin B12 deficiency, opioid use disorder or bacterial infection)

There is a second pathway that breaks down levodopa, via the enzyme catechol-O-methyltransferase (COMT)

2006) lends itself to being applied alongside conventional treatments to improve both understanding and biomechanical outcomes