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290 With aging, mitochondrial dysfunction and genomic instability can lead to the buildup of oxidative stress and DNA damage, which can disrupt energy production and genomic maintenance in motor neurons, processes implicated in ALS pathogenesis

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Starting at lower doses allows assessment of individual tolerance and response before potentially increasing the dose

3,12 Absorption and Distribution of Glutathione Little is known about the average daily intake of GSH, the amounts of GSH in various food sources, or the importance of dietary GSH in health or disease

bioRxiv2025 Jul 18

Proc Natl Acad Sci U S A , 1997