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A 2025 safety study confirmed IV BPC-157 was well tolerated in healthy adults with no adverse events

Xu B, Ji Y, Yao K, Cao YX, Ferro A (2005) Inhibition of human endothelial cell nitric oxide synthesis by advanced glycation end-products but not glucose: relevance to diabetes

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Glutathione supplementation is generally well-tolerated at typical doses (5002000 mg daily), though safety profiles differ across formulations and populations