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Clashes between protein and lipid atoms were reduced through 2500 conjugate-gradient minimization steps, followed by a 6 ns long MD simulation with a linearly-released positional constraint of 1 kcal mol 1 2 on protein and lipid phosphorus atoms

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It is the acetylated heptapeptide Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln, corresponding to residues 17-23 of native T4 (43 amino acids)

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