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Various monoclonal antibodies have been developed to block c-Met/HGF signaling pathways, some of which competitively bind to c-Met, and the others are served as traps for c-Met, preventing ligand attachment and dimerization of c-Met [168]

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Kidney-selective prodrugs of 6-mercaptopurine: biochemical basis of the kidney selectivity of S -(6-purinyl)-L-cysteine and metabolism of new analogs in rats

Arrait EM, Al-Ghafari AB, Al Doghaither HA

Benucci M, Bernardini P, Coccia C, et al

[PubMed] [Google Scholar] 93.Chen Z, Wang X, Shao Y, Shi D, Chen T, Cui D, et al