Glucagon-like peptide 1 reduces endothelial dysfunction, inflammation, and oxidative stress induced by both hyperglycemia and hypoglycemia in type 1 diabetes
Although research on liver injury and ferroptosis has shown promising results, it is mainly at the level of animal models, and there is a long way to go before clinical translation
Interestingly, GLP-1 receptor agonists oppose sympathetic effects on cardiac ventricular excitability, reducing ventricular arrhythmic risk through stimulation of cardiac parasympathetic neurons
A recent study demonstrated that Lobetyolin disrupts Gln metabolism by downregulating SLC1A5 expression in MDA-MB-231 and MDA-MB-468 breast cancer cells, induces apoptosis in these cells and exerts anti-tumor effects (83)
High-plex protein and whole transcriptome co-mapping at cellular resolution with spatial CITE-seq
An open label, randomized controlled study of oral calcitriol for the treatment of proteinuria in patients with diabetic kidney disease