The evidence was based on experimental data only briefly described in the patent and included models of: gastric ulcers, heart damage, liver damage, pancreatic injury, kidney damage, experimental diabetes, fever, edema, rhinitis, bone fracture, burns, skin wounds, hypersensitivity reactions, pupil dilation, colon injury, tumour growth, radiation injury, red blood cell development, fertility and lactation, tooth damage, several types of central and peripheral nerve damage, and survival from infection with Trichinosis (i.e., tapeworms) as well as several viruses
[DOI] [PMC free article] [PubMed] [Google Scholar] 3.Pickart L The human tri-peptide GHK and tissue remodeling
Specifically, SIRT1, SIRT3, and SIRT5 protect the cell from ROS, and SIRT2, SIRT6, and SIRT7 modulate oxidative stress 138,139
Skin Sensitivity If you're using topical GHK-Cu alongside semaglutide, be aware that caloric restriction and weight loss can sometimes make the skin more sensitive
Zhu B, Ba H, Kong L, et al
DNA repair: NAD+ serves as a coenzyme for enzymes involved in DNA repair, such as poly(ADP-ribose) polymerases (PARPs) and sirtuins