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However, some individuals have reported experiencing side effects such as cramping, bloating, and depleted zinc levels

PMID: 7987362

Elevations of the intermediate S-Adenosylhomocysteine (SAH) lead to a feed back inhibition of the function of the cycle and also a reduction in the transsulfuration pathway leading to a deficiency in the production of cysteine and glutathione (James)

Incorporation of Ga(III) in place of iron disrupts the iron-dependent redox process as Ga(III) cannot be reduced to Ga(II) under physiological conditions, and thus cannot be liberated from porphyrins by haem oxygenase ( A

The first class of antioxidants (e.g., uric acid, vitamin E and glutathione) inhibit the chain reaction of oxidation, acting as acceptors of free radicals and thus preventing/decreasing radical propagation