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It appears that maintaining adequate blood levels of the vitamin, like through supplementation, does improve birth outcomes ( SUMMARY A vitamin B12 deficiency can cause a range of mild to severe side effects, including anemia, weakness and fatigue, and birth defects in infants

Store solutions at 4C for short-term use (a few days) or freeze aliquots at -20C for longer periods

But when you start looking at actual dosing protocols, everything gets murky fast

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