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High prevalence of cobalamin deficiency in Guatemalan schoolchildren: associations with low plasma holotranscobalamin II and elevated serum methylmalonic acid and plasma homocysteine concentrations

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Cell culture studies have shown that NNMT inhibition increases intracellular NAD+ levels, enhances sirtuin activity, and shifts adipocyte metabolism toward greater fatty acid oxidation

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Description 5-Amino-1MQ is a small-molecule NNMT inhibitor investigated in experimental models of cellular energy metabolism and adipose-tissue regulation

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