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Under the influence of thiolase (acetyl-CoA acetyltransferase 1, ACAT1), CoA-SH is detached from one molecule of acetyl-CoA, and acetoacetyl-CoA (AcAc-CoA) is formed

J Diabetes Res 2016:4370490

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Potentially, also the encounter of HBsAg on hepatocytes may have facilitated the stimulation and expansion of transferred, stably TCR-expressing T cells before encountering the immunosuppressive tumor microenvironment