By the time it passes through the digestive tract, very little of the original glutathione remains intact to do its job
Shis group developed a biomimetic nanoparticles by modifying angiopep-2 to the surface of red blood cell membranes to camouflage polymer which was pH-sensitive and coload with anti-cancer drug DOX and BBB regulator lexiscan (Fig
Alternatively, NAR can be hydrolyzed by uridine hydrolase (URH1) into NA 38
2011;65(5):S38
Glutathione is widely found in animals and plants, and the contents of the bread yeast, wheat germ and animal liver are very high,100~100 mg/1000 g;Content is also rich in human and animal blood, such as human blood contains 26~34 mg/100 g, chicken blood contains 58-73 mg/73 g, pig blood contains 10~15 mg/100 g, the dog blood contains 14~22 mg/100 g.Many vegetables, potato and corn also contains GSH (see table 1)
doi: 10.1186/s13041-020-0559-8 159 DaiQDWuKSXuLPZhangYLinNJiangYet al