Distinct subsets of glial cells, termed disease-associated astrocyte (DAA) and disease-associated microglia (DAM), have been identified in both human patients and AD mouse models (Figures 1, 3
The core mechanism lies in synergistically promoting anabolic processes while inhibiting catabolic processes, thereby jointly maintaining cartilage homeostasis
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Research from the National Institutes of Health (NIH) highlights that physical therapy is particularly beneficial for individuals recovering from chronic pain conditions, post-injury recovery, and surgical rehabilitation
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