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IGF-IR promotes tumor growth, anoikis evasion, and metastasis PI3K is a classical lipid kinase that catalyzes the production of phosphatidylinositol-3,4,5-trisphosphate (PtdIns-3,4,5-P 3 ) [44]

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SP was supported by the Postgraduate Study Support Grant of the Faculty of Medicine, Khon Kaen University, Thailand, and the Invitation scholarship, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand (IN66038)