12: 1393407 Cribb AE, Lee BL, Trepanier LA, et al
doi: 10.3390/ijms20020420 86 ZhouL
Current PSMA-directed strategies encompass radioligand therapies (e.g., 177Lu-PSMA-617, 225Ac-PSMA-RLT), antibody-drug conjugates (MLN2704, PSMA-MMAE), cellular immunotherapies (PSMA-CAR-T, BiTEs), and experimental modalities such as photodynamic therapy and ultrasound-mediated nanobubble ablation
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While DSIP functions as a broad neuromodulator within central nervous system signaling pathways, Epitalon and Orexin represent more targeted models of circadian regulation, cellular aging processes, and arousal signaling
Using eye lens and lens epithelial cells (LECs), one of the best biological systems for study of molecular mechanisms of age-related diseases, we found that an age-associated decline in Prdx6 expression was linked to the loss of Nrf2