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Cagrilintide is linked to amylin signaling, while semaglutide targets GLP-1 receptor signaling

While freezing at -20C can extend stability beyond 28 days, the freeze-thaw process itself causes mechanical stress that can denature peptides

This modification alters the conformation and biological functions of target proteins

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Using chitosan, hyaluronic acid, alginate, and gelatin-based smart biological hydrogels for drug delivery in oral mucosal lesions: a review